Cardiomyopathy Cerebrovascular Disease (Stroke)

Stroke is caused by the blockage or rupture of blood vessels that supply the brain, causing a sudden loss of oxygen to the victim’s brain cells. Brain cells within the vicinity of the broken vessel are damaged within minutes and begin to die within hours. Stroke victims often experience a loss of body function and, depending upon the brain region affected, can suffer partial paralysis and sensory defects.



Human and Social Costs
Heart disease and stroke remain two of the top killers of Americans and pose a significant threat to millions of others, according to the American Heart Association's Heart Disease and Stroke Statistical Update 2014, published in its journal Circulation. The update reflects the most up-to-date statistics on heart disease, stroke, other vascular diseases and their risk factors. It is the only source for current prevalence data on cardiovascular health. Heart disease is the No. 1 cause of death in the U.S. and stroke is the No. 4 cause. The association compiles this update with the Centers for Disease Control and Prevention, the National Institutes of Health and other government agencies.


•    Stroke is the No. 4 cause of death in the United States, killing more than 129,000 people a year.
•    Stroke kills someone in the U.S. about once every four minutes.
•    Over the past 10 years, the death rate from stroke has fallen about 36 percent and the number of stroke deaths has dropped about 23 percent.
•    About 795,000 people have a stroke every year.
•    Someone in the U.S. has a stroke about once every 40 seconds.
•    Someone in the U.S. dies from a stroke every four minutes.
•    Stroke causes 1 of every 19 deaths in the U.S.
•    Stroke is a leading cause of disability.
•    Stroke is the leading preventable cause of disability.
•    African-Americans have nearly twice the risk for a first-ever stroke than white people, and a much higher death rate from stroke.

Although heart disease and stroke are often thought to primarily affect men and older people, they are also major killers of women and people in the prime of life.

Potential for Cures

Regenerative medicine technologies are bringing new hope for repairing the debilitating effects of stroke through the use of living cells and tissues.  Many companies are sponsoring with enrolling, ongoing, or completed clinical trials studying the use of autologous or allogeneic mesenchymal bone marrow cells, neural stem cells, and human-placenta derived cells to restore damaged brain tissue. Read more about stroke and regenerative medicine.