James F. Martin, MD, PhD

James F. Martin, M.D., Ph.D.
Vivian L. Smith Professor of Regenerative Medicine
Department of Molecular Physiology and Biophysics
Baylor College of Medicine
Director Cardiomyocyte Renewal Laboratory
Texas Heart Institute
(Houston, Texas)

Dr. Martin is a developmental biologist doing important work that has identified genes that block the heart from generating new heart muscle cells in laboratory mice shortly after their birth. Understanding the intricacies of how this inherent growth program works and how to safely “turn it back on” could lead to new therapies in which hearts damaged by heart attacks regenerate themselves.

Dr. Martin joined the Texas Heart Institute from Texas A&M System Health Science Center. In addition to working at THI, Dr. Martin collaborates with Texas Children's Hospital and the Baylor College of Medicine on developmental projects.

“We are interested in understanding how developmental pathways are connected to adult tissue regeneration. We are investigating the Hippo, Wnt, and Bmp-signaling pathways for developmental and regenerative capabilities. Our goal is to obtain an in depth understanding of these pathways in order to develop ways to regenerate heart muscle and craniofacial bone.”