Paul S. Knoepfler, PhD

Associate Professor
Cell Biology & Human Anatomy
Genome Center, Cancer Center
Institute for Regenerative Cures
School of Medicine
University of California, Davis
(Davis, California)

Dr. Paul Knoepfler is an Associate Professor in Cell Biology and Human Anatomy at the UC Davis School of Medicine, and a faculty member of the UC Davis Genome Center, Cancer Center (where he is the leader of the Cancer Stem Cell Initiative) and  the Institute for Regenerative Cures. Dr. Knoepfler is also an Assistant Investigator of the Institute for Pediatric Regenerative Medicine at Shriners Hospital of Northern California. Dr. Knoepfler did his postdoctoral training focused on Myc chromatin function in stem and tumor cells in Bob Eisenman’s Lab at the Fred Hutchinson Cancer Research Center in Seattle with support from a fellowship from the Jane Coffin Childs Memorial Fund for Medical Research and a Special Fellowship from the Leukemia and Lymphoma Society. He received his Ph.D. from UCSD School of Medicine in Molecular Pathology with support from a Lucille P. Markey Fellowship. He received his B.A. in English Literature from Reed College in Portland, OR.

Dr. Knoepfler's research interests include understanding what controls stem and cancer cell biological behavior. His lab is analyzing how the pluripotency control machinery goes awry during cancer as well as genomic and epigenomic events that inflence pluripotency and tumorigenicity with a particular interest in pediatric nervous system tumors and glioblastoma.